![]() ![]() This will create an upmarket atmosphere where everyone will feel spoilt. Decorate your activity room to look like a Day Spa, bring in items from home like paintings, candles, chandeliers and oil burners. Send out invitations to this special mothers day event. If you’re looking for a piece that is both elegant and meaningful to show your appreciation this Mother’s Day, there is perhaps no option better than this.įind out more about Harry Winston’s Forget-Me-Not Twin Ring here. Key Points for creating a beautiful Day Spa Room. ![]() Our treatments draw toxins out of your body to Promote a natural state of health. Your journey will take you on a stress relieving path with customized massages, body scrubs, & replenishing skin nourishment. Our goal at Contour Day Spa is to take you to a state of well-being. An exquisite ode to Mother Earth’s gifts, the Forget-Me-Not Twin Ring quickly stands out amongst the brand’s gorgeous floral-inspired gems. Contour Day Spa Plantation FL opened it's door in. The latest addition to the jewellery house’s timeless Forget-Me-Not Collection, the ring continues Harry Winston’s long-standing tradition of drawing inspiration from nature and melding it with the world’s most spectacular gemstones. To help you celebrate all mothers We have extended our offers. Performed only by specially trained Massage Therapists. A stunning medley of round brilliant, pear-shaped and marquise stones come together to form each ethereal bloom-the elegant silhouette of its namesake flower reimagined through delicate, sparkling jewels. This treatment uses a waterless body scrub and contour balm combined with firming massage techniques. Available in pink sapphires, blue sapphires or rubies, each vibrant bloom is set beside a complementary diamond flower on a minimal platinum setting. With two delicate wildflowers in perennial bloom, Harry Winston’s new Forget-Me-Not Twin Ring captures the magic of nature at its most enchanting. Explore the seasonal spa offerings from Salamander Resort & Spa. ![]()
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![]() Bane and Catwoman from the third film are also playable. Play as the legendary Dark Knight and Commissioner Gordon, as well as the Joker and his goons as they chase down Harvey Dent's police escort. The Dark Knight Pack (available 11/11/14)Įxperience the heart-pounding chase scene from the iconic film complete with cool vehicles and explosive action. Each pack can be purchased separately at $2.99/pack. The Season Pass will be available for the PS4, Xbox One, Xbox 360, PS3, and PC for a great price of $14.99. The first three of the DLC packs will be available on November 11 and 3 more will be announced at a later date. Players will be able to unlock a total of over 40 characters, vehicles, achievements and more. The Season Pass will include 6 DLC packs each with a unique themed mission level with story and free play modes. Interactive Entertainment revealed a DLC Season Pass for LEGO Batman 3: Beyond Gotham – the first Season Pass for a LEGO videogame. The game will also be featured in a PS3 bundle, slated to launch with the game. ![]() Lego Batman 3: Beyond Gotham will launch November 11 for PS4, Xbox One, Xbox 360, PS3, PC, Vita, Wii U and 3DS. Each piece of DLC can be purchased individually for $2.99. ![]() Future packs will include new playable characters, vehicles and levels. ![]() The latter has players following the exploits of the Joker and Harley Quinn as they set up "a variety of celebration set pieces," then play as the varying Batmans (Batmen?) through the hero's many years of existence. The DLC packs set to arrive alongside the game are The Dark Knight Pack, the Man of Steel Pack and the Batman 75th Pack, each with themed missions with story elements and free play modes. It will be available to PS4, Xbox One, PS3, Xbox 360 and PC owners, but not Wii U, 3DS and Vita. The season pass costs $14.99 and promises access to six add-ons in total, three of which will be announced at a later time. When Lego Batman 3: Beyond Gotham launches in November, players will have three pieces of DLC to pick up, each part of a season pass for the game. ![]() ![]() ![]() Secondly, plug the USB cable into another port of the computer to test whether it is available, or change a USB cable and try it again. As such, you need to try the following operation.įirstly, check your devices: (for iPhone: iOS 4.2.1 or higher for Android phone: Android 4.3 or above for PC: XP or up and for Mac: Mac OS X 10.5+). Sometimes, Smart Switch unable to connect to device. Subsequently, after confirming those operations, please restart the Samsung Smart Switch to test it again.īesides, if you run Samsung Smart Switch on PC or Mac, you need to establish a connection between the phones and computer first. Then reset the network of devices, restart your phones and try to connect them. If you use the latter at first, you need ensure that the WiFi of the devices is turned on respectively, and they are within the same WiFi network if possible. Samsung Smart Switch supports both USB and wireless (WiFi) connection. Samsung Smart Switch Failed to Connect the Device ![]() Now, we will analyze some common scenarios of Samsung Smart Switch not working problem and come up with some related suggestions. Although Smart Switch is an important tool to switch data from one device to Samsung phone, its compatibility and other performance really needs to be improved. The question above is selected from the Smart Switch Forum, and the doubt raised by an anonymous user is representative. ![]() ![]() ![]() Now I use both Keychain and Bitwarden: Keychain for passwords which sync across devices and Bitwarden for items that cannot be held in. We'll always be marked by an official flair, and will always love both 1Password and you. I used to use 1Password but migrated to Bitwarden (free). You'll see some friendly people from the 1Password team ready to help you - keep an eye out for /u/1PasswordCS-Blake, /u/agben, u/Zatara214, and more of us! Available on all major platforms, Enpass offers a comprehensive set of password management features to keep your online accounts secure. We know not everyone is comfortable storing their passwords on someone else’s servers, and that applies to businesses too. Read recent coverage on us and see the 1Password love. Businesses and large enterprises can now use Enpass to secure the passwords and sensitive data of their teams, and yes we are still OFFLINE.Bits will be marked by an official flair. ![]()
![]() I have tried removing noise with photoshop and with On 1 photo Raw and both these software cannoit oibtain the results you can obtain with Topaz denoise 6.Īnother example is accentuation. Results : when removing joise with Denoise 6 yoiu obtain an outstnading result and you keep the image sharp. Topaz Plug ins can achieve results far better than Photoshop or ON & PHoto RAW : example: Topaz Denoise 6: This is a complex plug in with Several filters and 11 sliders. ![]() I would ask what it is that you do in Topaz that you can't do in On1 Raw? Perhaps there are adjustments in RAW that you are not aware of? Hi Bernard, I appreciate that you have experience with and a comfort level with Topaz. I have a window system and would be happy to know if some of you have been able to access directly the Topaz plug ins from On 1 photo Raw and go back from Topaz plug ins into On 1 photo Raw without sending the pictures in a file to register it. or at least I was not able to set my computor to do it directly. Going in and out directly from On 1 photo to Topaz and vice versa seems impossible. When using Photoshop, going in and out of Topaz is straighforward.īut when using ON 1 photo Raw using the Topaz plug ins is not so easy. In addition to Photoshop I use very frequently Topaz plug ins such as Topaz denoise, topaz detail, topaz adjust, topas glow etc. I have been using photoshop for years but I recently discovered On 1 photo Raw and I found postprocessing was more pleasant and efficient with ON 1 photo Raw. ![]() ![]() ![]() ![]() With the advancement of these drugs, cases of long-term survival and profound responses in ESCC with distant metastases have been observed. Furthermore, the KEYNOTE-590 and CheckMate 648 trials showed the superiority of the anti-PD-1 antibody and chemotherapy combination group over the chemotherapy alone. In recent years, the efficacy of immune checkpoint inhibitors has been reported in several cancer types, and the efficacy of nivolumab, an anti-programmed death (PD)-1 antibody, has been demonstrated in the second-line treatment of esophageal cancer. Particularly, the add-on effects of anti-epidermal growth factor receptor (EGFR) antibodies, such as cetuximab and panitumumab, have been studied however, no superiority has been shown. To date, efficacy drugs in combination with FP therapy have been studied in several clinical trials. The combination of cisplatin and 5-fluorouracil (FP) has been considered the standard treatment for chemotherapy in cases of ESCC with distant metastasis. Ĭhemotherapy is the standard of care in cases of ESCC with distant metastasis, where the performance status is good and there is no obstruction. Conversion surgery following chemotherapy or chemoradiotherapy has been considered a promising strategy for improving the prognosis of patients with locally advanced ESCC. The primary treatment for esophageal squamous cell carcinoma (ESCC) without distant metastasis is surgery, which can include esophagectomy, radiation therapy, and chemotherapy. Squamous cell carcinoma accounts for the majority of the histological classification of esophageal cancer in Japan. It is the ninth most common cancer worldwide and the sixth leading cause of cancer-related death. ConclusionsĬonversion surgery following preoperative therapy, including immunotherapy, may be an effective treatment strategy for improving survival in patients with esophageal squamous cell carcinoma even among older adult patients.Įsophageal cancer is a highly aggressive disease and is often diagnosed at a locally advanced or metastatic stage. The patient had no recurrence 10 months postoperatively without adjuvant chemotherapy. Histological examination revealed complete response with no residual tumor or lymph node metastasis. ![]() The lymph node at the dorsal side of the IVC was not resected, and the left supraclavicular lymph node was removed. The patient underwent thoracoscopic subtotal esophagectomy and regional lymph node dissection. After four pharmacotherapy courses, primary tumor and metastatic lymph node shrinkage was observed. She was treated with pembrolizumab, cisplatin, and 5-fluorouracil. She was diagnosed with esophageal squamous cell carcinoma with distant metastasis of the lymph node at the dorsal side of the IVC and the left supraclavicular lymph node. Case presentationĪn 80-year-old woman presenting with difficulty swallowing was referred to our hospital. Here, we report a case of an older adult patient with esophageal squamous cell carcinoma who underwent surgery following combined treatment of immunotherapy and chemotherapy and achieved pathological complete response. Chemotherapy and chemoradiotherapy are common treatments for esophageal squamous cell carcinoma with distant metastasis however, the prognosis remains poor, and complete remission is difficult to achieve. ![]() ![]() ![]() It is not – and we won’t add it any time soon. We will first look at situations when people want to use dual axis charts, then we explain their problems, and afterward we’ll look at four alternatives: Why people use dual axis charts We’re sorry if that makes our user’s life harder, but we agree with the many chart experts who make cases against dual axis charts. Why do people use dual axis charts? We looked around and found that most people used them to show…ġ …two data series with the same measure, but different magnitudes, e.g. the global GDP on one axis and the GDP of Germany on the other one:Ģ …two data series that show the relative and the absolute values of something, e.g. the GDP per capita on one axis and the absolute GDP on the other one:ģ …two data series for totally different values, e.g. The GDP of a country on one axis and the life expectancy of that country on the other one:Ĥ …one data series, but the y-axis shows different scales, e.g. The values in Fahrenheit on one axis and in Celsius on the other one:Īs you can see, dual axis charts are often used to show two different data series with a different magnitude (=number range) and/or measure (GDP, life expectancy, etc). Often, their goal is to compare two trends with each other. Giving readers the possibility to do so makes a lot of sense – but there are some reasons why a dual axis chart is not the way to go. Let’s have a look at the problems with dual axis charts before thinking about alternatives: The problems with dual axis charts In fact, of these four use cases, we think that only the last dual axis chart can be used without any doubt, since it only uses the second Y-axis to show an alternative scale and not a second data series. Let’s use some real Worldbank data for the German GDP and the global GDP between 20 to explain that: Here’s the problem in a nutshell: The scales of dual axis charts are arbitrary and can therefore (deliberately) mislead readers about the relationship between the two data series. This chart has two different y-axes: The left axis shows the global GDP with a range from $40 to $80 trillion. The right axis shows the German GDP with a range between $2.5 and $4 trillion. A second axis sounds like a good solution – but there are three problems we have with them: Zero baselines at different heights can mislead The measure (US-Dollar) is the same, but we have a wildly different magnitude. ![]() The proportions of the two scales are often different from each other in dual axis charts. If the left axis would go down to zero, the chart would be twice as long. This is how both axes look like when we extend them to zero: If the right axis would go down to zero, the chart would be almost three times as long. So while the chart looks like the German GDP and the global GDP go up at roughly the same rate (at least until 2014), they don’t. The global GDP increased by 80% until 2014 the GDP of Germany by 40%. Most readers are used to line charts with just one scale. So when they see a line chart with two scales, their intuition goes into the normal “that’s how I read a line chart”-mode: “Oh, two lines, cool, same rate, interesting”. Readers actively need to remind themselves that these two lines have less of a relationship than they’re used to seeing in a line chart. So how small is the relationship between these two lines? Let’s go crazy. ![]() ![]() ![]() The American business letters use the below salutations. "Finding your person in the middle of all of this and experiencing that love when you're going through hell is the most beautiful thing I've ever experienced," she told the Times. All formats of business letters use the salutation except the Simplified Letter and the Memo. Recipient Address The address should include: Full name Job title Company Address City. The fallen entrepreneur met Evans in 2017, as Theranos was collapsing. If your contact information is included on the letterhead, your business letter starts with the date. ![]() ![]() Holmes' partner, Billy Evans, and her two young children also appear throughout the profile. The 39-year-old became known for her trademark black turtleneck, red lipstick, messy blonde hair and (as it turns out, false) masculine voice, traits that she admitted to the Times weren't "authentic." A business letter is a professional, formal letter that is sent by one company to another. She was due to report to prison last month, but filed a last-minute appeal that bought her more time. Holmes was convicted of four counts of fraud and conspiracy in January 2022 and was handed an 11-year prison sentence. Our business letter template can be used for any kind of professional communication, including writing a cover letter or a letter of interest. Further, a business letter starts with a salutation. Carreyrou reported in 2015 that these claims were false, triggering regulatory investigations and a lawsuit filed by the SEC. It is the standard to salute a person in a business letter with the. Hence, a good business letter is characterized by courtesy, convincing ability, knowledge and politeness. Holmes experienced a spectacular downfall after then-Wall Street Journal reporter John Carreyrou dug into claims made by her $9 billion health-tech startup, Theranos, that it had invented blood-testing devices that only required tiny amounts of blood. Choosing the right salutation can make all the difference and help you make a great first impression. Account icon An icon in the shape of a person's head and shoulders. How to Start a Letter: Professional Greeting Examples Starting a letter with the appropriate professional greeting sets the tone for the entire message and conveys respect to the recipient. ![]() ![]() This way, you can avoid any system-related technical issues. In addition, you can check the minimum system requirements of the emulator on the official website before installing it. If you follow the above steps correctly, you should have the PicFrame - Photo Collage ready to run on your Windows PC or MAC. If you do not want to download the APK file, you can install PicFrame - Photo Collage PC by connecting your Google account with the emulator and downloading the app from the play store directly. PicFrame was created with the aim of bringing old, discarded tablets back to life as digital picture frames: put your tablet on the wall, and use PicFrame to watch a slideshow of your photographs.Open PicFrame - Photo Collage APK using the emulator or drag and drop the APK file into the emulator to install the app.Download PicFrame - Photo Collage APK to your PC.Firstly, download and install an Android emulator to your PC.So it is advised that you check the minimum and required system requirements of an Android emulator before you download and install it on your PC.īelow you will find how to install and run PicFrame - Photo Collage on PC: However, emulators consume many system resources to emulate an OS and run apps on it. There are many free Android emulators available on the internet. PicFrame - Photo Collage is an Android app and cannot be installed on Windows PC or MAC directly.Īndroid Emulator is a software application that enables you to run Android apps and games on a PC by emulating Android OS. In addition, the app has a content rating of Everyone, from which you can decide if it is suitable to install for family, kids, or adult users. PicFrame - Photo Collage requires Android with an OS version of 2.3 and up. It has gained around 10000000 installs so far, with an average rating of 4.0 out of 5 in the play store. If you ever prefer to go with Andy for PC to free download and install Picframe for Mac, you might still continue with the same method anytime.PicFrame - Photo Collage is an Android Photography app developed by Tiny Piece Co., Ltd and published on the Google play store. You’ll be able to install Picframe for PC making use of apk file if you cannot see the app on the google playstore by just clicking on the apk file BlueStacks App Player will install the app. Ultimately, you’ll be brought to google play store page this lets you do a search for Picframe app by utilizing the search bar and install Picframe for PC or Computer. Connect a Google account by just signing in, that will take couple of min’s.ħ. Within your windows start menu or alternatively desktop shortcut open up BlueStacks App Player.Ħ. If you see "Install" on screen, please click on it to start the final install process and then click "Finish" right after it’s finished.ĥ. ![]() Carry on with all the easy installation steps just by clicking on "Next" for a couple times.Ĥ. As soon as the installer completes downloading, open it to begin the set up process.ģ. Begin with downloading BlueStacks App player on your PC.Ģ. Just click on "Download Picframe APK" option to start downloading the apk file into your PC. It is really an easy task to install the emulator when you are all set and only needs few minutes. We advise you to preliminary see the suggested Operating system requirements to install the Android emulator on PC and then download and install given that your PC meets the suggested OS prerequisites of the emulator. To help you out we are going to recommend either Bluestacks or Andy android emulator, both of these happen to be compatible with windows and MAC OS. ![]() Out of many paid and free Android emulators available for PC, it’s not at all an quick step as you feel to get hold of the highest quality Android emulator which functions well on your PC. ![]() You’ll find couple of really important guidelines listed below that you will need to carry out before you start to download Picframe PC. launched Picframe app just for Google’s Android along with iOS however, you may possibly install Picframe on PC or computer. ![]() Since PicFrame was released on the iPhone and iPad we have often been requested to create a. With 73 adjustable frames, support for up to 9 photos in a single frame, rounded corners and plenty of border patterns, you will always have a unique look. Free Download Picframe for PC with this tutorial at AppsPlayground. PicFrame helps you combine multiple photos into amazing looking frames that you can save to your computer or share to Facebook Twitter and Flickr. ![]() ![]() On a tour, you'll probably see more per day than you would on your own. Good tours come with expert, passionate teachers for guides, small groups, and take full advantage of the built economy and efficiency that can come with group travel. After thirty years of tour guiding experience, I've found that for the right person, choosing the right tour, can reward that traveler with some of the best travel experiences possible. But for many travelers a guided bus tour can also be a good choice. Invest in a guidebook that fits your style. There are guidebooks for everyone: shoppers, opera buffs, seniors, campers.even vegetarians. Guidebooks - whether print or digital - are vital tools. Equipped with good information and a determination to travel smart, you can be your own tour guide. Many wish they could go on their own but are nervous about traveling independently. Going on your own gives you flexibility, freedom, and you can connect more intimately with Europe. You can explore Europe on your own or with a tour. When it comes to information, like anywhere, be a savvy consumer. Still, drop by to pick up a city map, learn about special events, and so on. Funded by hotels and big tour companies, they can be more interested in selling tickets and services than just giving information. But be aware, while handy, their purpose is to help you spend money in their town. All over Europe - wherever there are tourists, you'll find tourist information offices. During the Middle Ages, Venice was Europe's trading superpower, but today the big business is tourism. And for temperatures they use Celsius rather than Fahrenheit - here's a memory aid: 28 C is the same as 82 F.pretty warm. And you might as well make your numbers European style: cross your sevens because a one looks like this. For instance, one and a half kilos looks like this.and there's one thousand grams in a kilo. And when they write numbers, Europeans use commas and periods differently than we do. All over Europe produce - in this deli, cheese and meat - is sold in 100-gram increments - about a quarter pound - plenty for a hearty sandwich. Here's about half a kilo.that's roughly a pound. Weights and other measurements throughout Europe use the metric system. In order to travel well, you need to be engaged. By the way.cute little European hotels.often without elevators. So, their first floor is the American second.and their second floor is what we'd call the third. And over here the ground floor is.the ground floor. On forms, fill in the date European style:. Travel is fraught with cultural differences. The ancient Pantheon is mobbed through the day.but literally all yours early or late. Or you can arrange your schedule to avoid crowds. You can also make reservations - in places like Rome's Borghese Gallery - to get directly into crowded sights by phone or on the web. For example, these people at the Louvre in Paris could avoid this notorious line if they simply bought the city museum pass (which lets you go directly through the turnstyle). ![]() They're waiting to buy tickets to get in, but there are other ways to get tickets. Most lines you see - like this one at the Uffizi Gallery in Florence - are not people waiting to get in. To me, there are two kinds of travelers: those who waste valuable time waiting in long lines like this and smarter travelers who don't. With so many people traveling these days, if you're not on the ball, crowds can be a real problem. It'll take an hour for these folks to get into the church. Mark's Square - in mid-day - can come with overwhelming crowds. To be here, on this unique island, amid all this culture and history is truly a wonder. For most people, Venice is a must-see destination. In this second episode we travel through the highlights of Northern Italy: Venice, Siena, and the Cinque Terre - my favorite stretch of the Riviera. ![]() In this three-part travel skills special, we start in the Netherlands, venture through Germany, dip into Italy, sweep through Switzerland and France before finishing in England. Join the village parade, make new friends where there are no postcards. You find it best by becoming a temporary local. But you can go deeper than traditions put on display for tourists. And it's lots of fun snapping photos of the predictable biggies and checking out the cultural icons. ![]() Today more people than ever are enjoying Europe. The skills we'll cover in this episode: planning, packing, safety and - perhaps the most rewarding skill of all - connecting with locals. This time, we're going beyond the sights, bringing you more practical tips to help make your European trip fun and hassle-free. I'm Rick Steves - immersed in the wonders of Venice - and back for part two of our three-part travel skills special. ![]() |